Anand, a Pulitzer Prize-winning reporter for the Wall Street Journal, has written the story of one father's race against time to found a business that would cure his sick children. John and Aileen Crowley were on top of the world. With a brand-new Harvard Business School degree, three beautiful children, a new house, and a great job, they thought that they had just entered the best years of life. Then doctors diagnosed their two youngest children with Pompe disease, a degenerative disease so rare that no company had bothered spending the money needed to sponsor research.